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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Brien, R.J. | LF | Oakland Athletics | 37 | 04/18/2012 | Danbury | USA | Left | Left | 6' 2" | 205 lbs | $4,400,000 |
| O'Donnell, Sean | C | Free Agent | 17 | 05/28/2032 | Sioux City | USA | Right | Right | 6' 0" | 170 lbs | - |
| O'Reilly, Rick | 2B | Free Agent | 29 | 12/28/2020 | Toronto | CAN | Right | Right | 6' 2" | 200 lbs | - |
| O'Toole, Barrfhionn | RF | California Angels | 29 | 03/16/2020 | Roscrea | IRL | Left | Left | 6' 3" | 200 lbs | $675,000 |
| Oakes, Eric | RP | Chicago Cubs | 29 | 10/30/2020 | Mitchellville | USA | Right | Right | 6' 5" | 200 lbs | $3,520,000 |
| Ocasio, Juan | 2B | Washington Nationals | 18 | 09/28/2031 | Restrepo | COL | Right | Right | 6' 2" | 180 lbs | - |
| Ogle, Nick | LF | Cleveland Guardians | 27 | 08/28/2022 | Flora | USA | Right | Right | 6' 4" | 200 lbs | $6,600,000 |
| Ogren, Bill | RP | Colorado Rockies | 28 | 12/10/2021 | DeFuniak Springs | USA | Right | Left | 6' 2" | 200 lbs | $1,796,800 |
| Ohmer, Austin | CF | Montreal Expos | 27 | 07/17/2022 | St. Joseph | USA | Left | Right | 5' 10" | 195 lbs | $50,000,000 |
| Ohnn, Young-kwang | C | Free Agent | 31 | 05/04/2018 | Incheon | KOR | Right | Right | 6' 0" | 200 lbs | - |
| Omura, Katsumi | SP | Free Agent | 35 | 10/24/2014 | Ago | JPN | Switch | Left | 6' 1" | 180 lbs | - |
| Onate, Mike | 2B | Oakland Athletics | 18 | 12/05/2031 | Havana | CUB | Right | Right | 6' 3" | 175 lbs | - |
| Orosco, Omar | RP | Philadelphia Phillies | 25 | 05/01/2024 | Calexico | USA | Right | Right | 6' 4" | 205 lbs | $675,000 |
| Ortega, Darrell | RF | Los Angeles Dodgers | 29 | 06/08/2020 | Weymouth | USA | Left | Left | 6' 3" | 200 lbs | $675,000 |
| Ortega, Rich | RP | Free Agent | 40 | 08/27/2009 | La Vega | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Ortiz, Alberto | SP | Free Agent | 17 | 08/17/2032 | Brick | USA | Right | Right | 6' 5" | 190 lbs | - |
| Ortiz, Bill | C | Texas Rangers | 18 | 08/06/2031 | San Antonio Castillo Velasco | MEX | Right | Right | 5' 11" | 175 lbs | - |
| Ottinger, Corey | 3B | Free Agent | 35 | 11/06/2014 | Madison | USA | Right | Right | 6' 2" | 200 lbs | - |
| Ovens-Toots, Kevin | SP | Texas Rangers | 28 | 05/27/2021 | Lake Charles | USA | Right | Right | 6' 1" | 195 lbs | $22,000,000 |
| Overlie, Justin | RP | New York Mets | 25 | 02/20/2024 | Salt Lake City | USA | Right | Right | 5' 11" | 185 lbs | $1,459,350 |
| Overturf, Brad | CL | Free Agent | 16 | 01/24/2033 | St. Paul | USA | Left | Right | 6' 1" | 170 lbs | - |
| Oviedo, David | RP | Philadelphia Phillies | 22 | 04/02/2027 | Chesterfield | USA | Right | Right | 6' 2" | 200 lbs | - |
| Owens, John | RP | Free Agent | 29 | 07/21/2020 | Norristown | USA | Right | Right | 6' 3" | 200 lbs | - |
| Oxenrider, Alan | 3B | Chicago Cubs | 36 | 11/14/2013 | Lyman | USA | Right | Right | 6' 2" | 205 lbs | $4,000,000 |
