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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Eaker, Chris | RP | Kansas City Royals | 28 | 04/05/2020 | Amarillo | USA | Left | Left | 6' 0" | 200 lbs | $1,240,000 |
| Ealy, Vince | SS | Texas Rangers | 34 | 09/15/2014 | Arlington | USA | Switch | Right | 6' 4" | 200 lbs | $16,000,000 |
| Earnest, Curt | 2B | Free Agent | 37 | 11/20/2011 | Oconomowoc | USA | Right | Right | 6' 2" | 190 lbs | - |
| Eaton, Tommie | SS | Montreal Expos | 36 | 06/12/2012 | Sacramento | USA | Right | Right | 6' 6" | 205 lbs | $7,000,000 |
| Eberhart, Danny | SS | Free Agent | 33 | 02/28/2015 | Robert Lee | USA | Right | Right | 6' 1" | 205 lbs | - |
| Ebersole, Chris | SP | Free Agent | 17 | 05/12/2031 | Rock Island | USA | Right | Right | 6' 4" | 185 lbs | - |
| Edgar, George | SP | Free Agent | 17 | 06/03/2031 | Mississauga | CAN | Left | Left | 6' 1" | 175 lbs | - |
| Edwards, Harry | RP | Free Agent | 16 | 04/27/2032 | Great Yarmouth | ENG | Right | Left | 6' 0" | 170 lbs | - |
| Egami, Itsuo | 3B | Free Agent | 38 | 11/06/2010 | Kawaguchi | JPN | Right | Right | 6' 2" | 195 lbs | - |
| Ehret, Kyle | RP | California Angels | 34 | 03/05/2014 | Allentown | USA | Right | Right | 6' 2" | 200 lbs | $2,000,000 |
| Eismann, Marc | SP | St. Louis Cardinals | 23 | 07/09/2025 | Greenfield | USA | Left | Left | 6' 2" | 200 lbs | - |
| Eisner, Warren | 3B | Arizona Diamondbacks | 30 | 04/25/2018 | Oberlin | USA | Switch | Right | 6' 0" | 200 lbs | $5,650,000 |
| Ekdar, John | SP | Free Agent | 16 | 09/13/2032 | Quinte West | CAN | Right | Right | 6' 1" | 170 lbs | - |
| Ekwall, Dillon | SP | Free Agent | 17 | 08/25/2031 | Macedonia | USA | Right | Right | 6' 2" | 180 lbs | - |
| Eli, Arturo | SP | New York Yankees | 24 | 01/02/2024 | Bachaquero | VEN | Left | Left | 6' 2" | 200 lbs | $1,539,000 |
| Ellenberger, Tim | RF | Free Agent | 17 | 04/23/2031 | Escondido | USA | Left | Left | 6' 1" | 170 lbs | - |
| Elliott, Bob | SP | Free Agent | 17 | 05/08/2031 | Poplar Bluff | USA | Right | Right | 6' 0" | 170 lbs | - |
| Emchenko, Marko | RP | Baltimore Orioles | 31 | 05/13/2017 | Cherkasy | UKR | Left | Left | 6' 2" | 200 lbs | $5,000,000 |
| Encinias, Billy | C | Free Agent | 36 | 09/08/2012 | Brooklyn | USA | Switch | Right | 6' 1" | 195 lbs | - |
| Engelhardt, Justin | 3B | Free Agent | 37 | 04/10/2011 | Irvine | USA | Right | Right | 6' 1" | 195 lbs | - |
| Enriquez, Melvin | LF | St. Louis Cardinals | 23 | 04/13/2025 | Villa del Rosario | VEN | Right | Right | 6' 3" | 200 lbs | $675,000 |
| Eronilde, Trystão | SP | Free Agent | 15 | 03/27/2033 | Valencia | VEN | Right | Right | 6' 4" | 185 lbs | - |
| Escalante, Raul | RP | Free Agent | 16 | 04/08/2032 | Castelldefels | ESP | Left | Left | 6' 2" | 175 lbs | - |
| Escobosa, Antonio | RP | Baltimore Orioles | 25 | 07/26/2023 | Puebla | MEX | Right | Right | 6' 0" | 190 lbs | $1,200,000 |
| Esini, Lucan | CF | San Francisco Giants | 25 | 08/23/2023 | Vatican City | VCY | Right | Right | 6' 4" | 200 lbs | $3,080,000 |
| Esser, Corey | CL | Free Agent | 17 | 09/18/2031 | East Moriches | USA | Right | Right | 6' 3" | 185 lbs | - |
| Esteves, Nick | CF | Free Agent | 32 | 02/01/2016 | Santo Domingo | DOM | Right | Right | 6' 5" | 205 lbs | - |
| Estrada, Manny | 1B | Kansas City Royals | 28 | 11/01/2020 | Douglas | USA | Left | Left | 6' 8" | 200 lbs | $6,100,000 |
| Eubanks, Mike | C | Free Agent | 16 | 06/28/2032 | Swansea | USA | Right | Right | 6' 0" | 170 lbs | - |
| Evans, Matt | SP | Philadelphia Phillies | 34 | 08/16/2014 | Seattle | USA | Right | Right | 6' 4" | 205 lbs | $35,600,000 |
| Evans, Ryan | 1B | Free Agent | 17 | 04/18/2031 | Marana | USA | Left | Left | 6' 2" | 190 lbs | - |
| Everett, Elijah | RP | Oakland Athletics | 27 | 02/09/2021 | Dallas | USA | Left | Right | 6' 3" | 200 lbs | $675,000 |
