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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saez, Mario | LF | Norfolk Tides | 34 | 12/05/2010 | Rock Port | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sakamoto, Tatsumi | SP | Free Agent | 28 | 07/12/2016 | Toyama | JPN | Right | Right | 6' 4" | 200 lbs | - |
| Salazar, Franklin | RP | Omaha Storm Chasers | 22 | 10/24/2022 | Boca Chica | DOM | Right | Right | 6' 2" | 195 lbs | - |
| Salgado, Melvin | RF | Free Agent | 31 | 12/13/2013 | Caucagüita | VEN | Left | Left | 6' 1" | 195 lbs | - |
| Samano, Daniel | C | Memphis Redbirds | 27 | 02/25/2017 | Maravatío | MEX | Right | Right | 6' 1" | 200 lbs | - |
| Sammons, Mike | C | Round Rock Express | 32 | 04/12/2012 | Philadelphia | USA | Left | Right | 5' 9" | 200 lbs | - |
| Sams, Blake | LF | Pawtucket Red Sox | 22 | 04/16/2022 | Pegram | USA | Left | Left | 6' 0" | 200 lbs | - |
| Sanchez, Antonio | RP | Durham Bulls | 30 | 07/28/2014 | Saltillo | MEX | Left | Right | 6' 6" | 200 lbs | $625,000 |
| Sanchez, Juan | RP | Free Agent | 31 | 12/28/2012 | Zaza del Medio | CUB | Switch | Right | 6' 6" | 200 lbs | - |
| Sanchez, Kory | C | Lehigh Valley IronPigs | 24 | 03/16/2020 | Coon Rapids | USA | Right | Right | 6' 4" | 200 lbs | - |
| Santos, Antonio | RP | Omaha Storm Chasers | 22 | 10/31/2022 | Peapack & Gladstone | USA | Switch | Right | 6' 4" | 185 lbs | - |
| Sartores, Vasquo | RP | Albuquerque Isotopes | 32 | 09/04/2012 | Piracicaba | BRA | Left | Left | 6' 0" | 200 lbs | $625,000 |
| Saunders, Cedric | DH | Buffalo Bisons | 31 | 02/06/2013 | Bognor Regis | ENG | Left | Right | 6' 2" | 200 lbs | - |
| Savage, Jason | 3B | Free Agent | 33 | 07/02/2011 | Lakes of the Four Seasons | USA | Right | Right | 5' 10" | 185 lbs | - |
| Savell, Jake | LF | Charlotte Knights | 22 | 01/24/2022 | Albertville | USA | Right | Right | 6' 3" | 195 lbs | - |
| Saxman, Max | SS | Free Agent | 37 | 01/01/2007 | Jacksonville | USA | Right | Right | 6' 0" | 205 lbs | - |
| Schau, Jon | CL | Reno Aces | 24 | 07/23/2020 | Ithaca | USA | Right | Right | 6' 3" | 185 lbs | - |
| Schermerhorn, Mike | RF | El Paso Chihuahuas | 24 | 11/25/2020 | Eugene | USA | Left | Left | 6' 7" | 205 lbs | - |
| Schmiege, Jake | 2B | Free Agent | 30 | 10/11/2014 | Springfield | USA | Right | Right | 5' 11" | 190 lbs | - |
| Schneider, Aaron | RP | Norfolk Tides | 35 | 12/04/2009 | Industry | USA | Right | Right | 6' 1" | 200 lbs | - |
| Schonewille, Davey | CF | Gwinnett Braves | 30 | 10/16/2014 | Willemstad | CUR | Left | Right | 6' 3" | 195 lbs | - |
| Schumacher, Andy | C | Toledo Mud Hens | 23 | 10/29/2021 | Manchester | USA | Left | Right | 5' 10" | 190 lbs | - |
| Segarra, Jorge | SP | Albuquerque Isotopes | 34 | 07/20/2010 | Florida Ridge | USA | Left | Left | 6' 1" | 200 lbs | - |
| Seiffert, Kirk | SS | Free Agent | 26 | 11/05/2018 | Iowa City | USA | Right | Right | 6' 0" | 180 lbs | - |
| Seiler, Will | RP | Free Agent | 29 | 10/06/2015 | Chicago | USA | Right | Right | 6' 2" | 190 lbs | - |
| Seliger, Doug | SP | New Orleans Zephyrs | 24 | 12/27/2020 | Evansville | USA | Right | Right | 6' 3" | 200 lbs | $625,000 |
| Sell, Phil | SP | Free Agent | 24 | 10/30/2020 | Los Angeles | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sellars, Warren | RP | Free Agent | 37 | 01/02/2007 | Mississauga | CAN | Right | Right | 6' 2" | 200 lbs | - |
| Serrata, Ruben | RF | Free Agent | 23 | 12/04/2021 | Sabana Grande de Boya | DOM | Right | Left | 6' 3" | 195 lbs | - |
| Serrão, Cristiano | 1B | Free Agent | 31 | 12/29/2012 | Natal | BRA | Switch | Right | 6' 0" | 200 lbs | - |
| Sever, Erik | SP | Free Agent | 31 | 09/28/2013 | Mission | USA | Right | Right | 6' 3" | 200 lbs | - |
| Shafer, Brad | SP | Omaha Storm Chasers | 23 | 01/16/2021 | Old Town | USA | Right | Right | 6' 3" | 195 lbs | $625,000 |
| Shaffer, John | 3B | Free Agent | 27 | 08/15/2017 | Morrow | USA | Right | Right | 5' 9" | 195 lbs | - |
| Shanahan, Alan | RP | Gwinnett Braves | 33 | 03/26/2011 | Beaver Dam | USA | Right | Right | 6' 3" | 205 lbs | - |
| Shishido, Toshimi | C | Free Agent | 34 | 06/24/2010 | Tsukuba | JPN | Right | Right | 6' 0" | 195 lbs | - |
| Simmons, Chris | 3B | Memphis Redbirds | 24 | 07/19/2020 | Martinsville | USA | Right | Right | 5' 11" | 185 lbs | - |
| Sinden, Josh | LF | Nashville Sounds | 35 | 09/25/2009 | Safford | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sklavenitis, Tibalt | 2B | Free Agent | 26 | 05/11/2018 | Pafos | CYP | Left | Right | 5' 10" | 195 lbs | - |
| Smallwood, Jason | SP | Salt Lake Bees | 22 | 12/26/2022 | Petersburg | USA | Right | Right | 5' 10" | 195 lbs | - |
| Smith, Tyler | SP | Free Agent | 33 | 12/08/2011 | Vancouver | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sohn, Young-ghil | SP | Buffalo Bisons | 36 | 09/03/2008 | Gwangju | KOR | Right | Right | 5' 11" | 190 lbs | - |
| Solano, Ramiro | RP | Free Agent | 26 | 09/17/2018 | Managua | NCA | Switch | Right | 6' 3" | 200 lbs | - |
| Solis, Javier | C | Omaha Storm Chasers | 23 | 09/05/2021 | Rock Hill | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sonn, Mike | C | New Orleans Zephyrs | 32 | 09/21/2012 | Santa Fe Springs | USA | Right | Right | 5' 11" | 200 lbs | - |
| Soriano, Alejandro | CF | Free Agent | 27 | 07/05/2017 | Tifton | USA | Left | Right | 6' 4" | 200 lbs | - |
| Sousa, Ian | 1B | Free Agent | 31 | 12/28/2012 | Columbia | USA | Right | Right | 6' 0" | 185 lbs | - |
| Sousa, James | LF | El Paso Chihuahuas | 24 | 09/06/2020 | La Cañada Flintridge | USA | Left | Left | 6' 8" | 205 lbs | - |
| Spradling, Jason | 3B | Free Agent | 34 | 11/03/2010 | Worcester | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Stables, Johnny | C | Round Rock Express | 37 | 02/18/2007 | Houma | USA | Switch | Right | 6' 1" | 210 lbs | - |
| Stahlman, T.J. | RP | Tacoma Rainiers | 23 | 03/21/2021 | Austin | USA | Right | Right | 6' 4" | 200 lbs | $625,000 |
| Staley, Bob | 3B | Free Agent | 30 | 11/26/2014 | Akron | USA | Right | Right | 5' 9" | 185 lbs | - |
| Stanley, Stephen | RP | Oklahoma City Dodgers | 24 | 07/23/2020 | Rock Island | USA | Left | Right | 6' 2" | 195 lbs | $625,000 |
| Stark, Luke | 2B | Round Rock Express | 35 | 09/27/2009 | Unknown | USA | Right | Right | 6' 2" | 200 lbs | - |
| Steele, Brett | 2B | Rochester Red Wings | 30 | 08/31/2014 | Los Angeles | USA | Right | Right | 6' 3" | 205 lbs | $625,000 |
| Steggall, Helmut | C | El Paso Chihuahuas | 30 | 05/18/2014 | Saalfelden | AUT | Left | Right | 6' 0" | 210 lbs | - |
| Sterner, Jason | SP | Omaha Storm Chasers | 24 | 12/18/2020 | Dallas | USA | Right | Right | 6' 7" | 200 lbs | - |
| Stillions, Chris | 2B | Nashville Sounds | 32 | 08/31/2012 | Modesto | USA | Right | Right | 6' 0" | 200 lbs | - |
| Stinnett, Josh | 2B | Toledo Mud Hens | 26 | 11/12/2018 | Opelousas | USA | Right | Right | 5' 10" | 195 lbs | - |
| Stoll, Mike | RF | Free Agent | 32 | 05/08/2012 | Ardmore | USA | Right | Left | 6' 1" | 200 lbs | - |
| Stone, Pat | RP | Free Agent | 25 | 12/31/2018 | Charlotte | USA | Right | Right | 6' 0" | 185 lbs | - |
| Stoyle, Kai | SS | Free Agent | 32 | 07/31/2012 | Bull Savanna | JAM | Right | Right | 6' 2" | 190 lbs | - |
| Stratton, Shane | CL | Free Agent | 25 | 01/04/2019 | New York | USA | Right | Left | 6' 3" | 195 lbs | - |
| Straub, Josh | LF | Sacramento River Cats | 26 | 04/18/2018 | Sterling | USA | Left | Left | 6' 1" | 195 lbs | - |
| Strey, Mike | C | Buffalo Bisons | 32 | 03/21/2012 | Albuquerque | USA | Right | Right | 6' 4" | 200 lbs | - |
| Strijbis, Kennet | 2B | Free Agent | 32 | 12/17/2012 | Oranjestad | ANT | Right | Right | 6' 2" | 200 lbs | - |
| Stutzman, Matt | SP | Round Rock Express | 30 | 03/24/2014 | New York | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sugai, Yoriyuki | RP | New Orleans Zephyrs | 31 | 07/27/2013 | Oita | JPN | Left | Left | 6' 2" | 205 lbs | - |
| Sutton, Kurt | SP | El Paso Chihuahuas | 24 | 07/26/2020 | D'Iberville | USA | Left | Left | 6' 0" | 175 lbs | - |
| Sweet, Corbett | RP | Round Rock Express | 39 | 06/15/2005 | Brooklyn | USA | Left | Left | 6' 2" | 200 lbs | - |
